V49I (p.Val49Ile) variant of BCL6 (B-cell lymphoma 6 protein)
V49I (p.Val49Ile) in BCL6 (B-cell lymphoma 6 protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
V49I (p.Val49Ile) variant details
- p.Val49Ile
- cosmic curated COSV51650
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- REVEL 0.32
- CADD 23.40
- PolyPhen-2 0.96
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available