T12I (p.Thr12Ile) variant of BCL6 (B-cell lymphoma 6 protein)
T12I (p.Thr12Ile) in BCL6 (B-cell lymphoma 6 protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data.
T12I (p.Thr12Ile) variant details
- p.Thr12Ile
- Ensembl rs2108471713
- Missense
- Variant Prioritization Score for Impact Estimate 0.685
- REVEL 0.61
- CADD 27.30
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)