S59N (p.Ser59Asn) variant of BCL6 (B-cell lymphoma 6 protein)
S59N (p.Ser59Asn) in BCL6 (B-cell lymphoma 6 protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
S59N (p.Ser59Asn) variant details
- p.Ser59Asn
- cosmic curated COSV10608
- TOPMed rs1474668374
- gnomAD rs1474668374
- Missense
- Variant Prioritization Score for Impact Estimate 0.469
- REVEL 0.23
- CADD 26.80
- PolyPhen-2 0.52
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available