R140L (p.Arg140Leu) variant of BCL6 (B-cell lymphoma 6 protein)
R140L (p.Arg140Leu) in BCL6 (B-cell lymphoma 6 protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
R140L (p.Arg140Leu) variant details
- p.Arg140Leu
- 1000Genomes rs536118071
- ExAC rs536118071
- TOPMed rs536118071
- gnomAD rs536118071
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.26
- CADD 22.50
- PolyPhen-2 0.23
- SIFT 0.02
- Most common in the 1KG:ESN population (allele frequency 0.0049)