R122W (p.Arg122Trp) variant of BCL6 (B-cell lymphoma 6 protein)
R122W (p.Arg122Trp) in BCL6 (B-cell lymphoma 6 protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
R122W (p.Arg122Trp) variant details
- p.Arg122Trp
- cosmic curated COSV51651
- 1000Genomes rs551620719
- ExAC rs551620719
- TOPMed rs551620719
- Missense
- Variant Prioritization Score for Impact Estimate 0.462
- REVEL 0.43
- CADD 32.00
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the 1KG:STU population (allele frequency 0.0051)
- Structural context available