N73S (p.Asn73Ser) variant of BCL6 (B-cell lymphoma 6 protein)
N73S (p.Asn73Ser) in BCL6 (B-cell lymphoma 6 protein) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data.
N73S (p.Asn73Ser) variant details
- p.Asn73Ser
- rs760006045
- NCI-TCGA Cosmic COSV5165
- cosmic curated COSV51650
- ExAC rs760006045
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.17
- CADD 23.00
- PolyPhen-2 0.95
- SIFT 1.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 0.00048)