H116R (p.His116Arg) variant of BCL6 (B-cell lymphoma 6 protein)
H116R (p.His116Arg) in BCL6 (B-cell lymphoma 6 protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
H116R (p.His116Arg) variant details
- p.His116Arg
- gnomAD rs1218169171
- Missense
- Variant Prioritization Score for Impact Estimate 0.643
- REVEL 0.64
- CADD 26.60
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available