V25A (p.Val25Ala) variant of BCL11B (B-cell lymphoma/leukemia 11B)
V25A (p.Val25Ala) in BCL11B (B-cell lymphoma/leukemia 11B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
V25A (p.Val25Ala) variant details
- p.Val25Ala
- TOPMed rs897884211
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.06
- CADD 22.30
- PolyPhen-2 0.01
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available