S101T (p.Ser101Thr) variant of BCL11B (B-cell lymphoma/leukemia 11B)
S101T (p.Ser101Thr) in BCL11B (B-cell lymphoma/leukemia 11B) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes structural context.
S101T (p.Ser101Thr) variant details
- p.Ser101Thr
- rs1383379624
- ClinGen CA390939028
- ClinVar RCV002469845
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- AlphaMissense 0.06
- MetaLR 0.02
- MetaSVM -1.03
- PolyPhen-2 0.00
- SIFT 0.58
- MutPred 0.18
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available