Q149K (p.Gln149Lys) variant of BCL11B (B-cell lymphoma/leukemia 11B)
Q149K (p.Gln149Lys) in BCL11B (B-cell lymphoma/leukemia 11B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
Q149K (p.Gln149Lys) variant details
- p.Gln149Lys
- ExAC rs752560767
- gnomAD rs752560767
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.15
- CADD 19.10
- PolyPhen-2 0.00
- SIFT 0.99
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available