P51L (p.Pro51Leu) variant of BCL11B (B-cell lymphoma/leukemia 11B)
P51L (p.Pro51Leu) in BCL11B (B-cell lymphoma/leukemia 11B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
P51L (p.Pro51Leu) variant details
- p.Pro51Leu
- cosmic curated COSV10591
- TOPMed rs1889213308
- gnomAD rs1889213308
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.14
- CADD 22.90
- PolyPhen-2 0.03
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available