P20S (p.Pro20Ser) variant of BCL11B (B-cell lymphoma/leukemia 11B)
P20S (p.Pro20Ser) in BCL11B (B-cell lymphoma/leukemia 11B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
P20S (p.Pro20Ser) variant details
- p.Pro20Ser
- TOPMed rs1228198631
- gnomAD rs1228198631
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.11
- CADD 23.20
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available