L128F (p.Leu128Phe) variant of BCL11B (B-cell lymphoma/leukemia 11B)
L128F (p.Leu128Phe) in BCL11B (B-cell lymphoma/leukemia 11B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
L128F (p.Leu128Phe) variant details
- p.Leu128Phe
- TOPMed rs1889201013
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.06
- CADD 21.10
- PolyPhen-2 0.31
- SIFT 0.16
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available