I141V (p.Ile141Val) variant of BCL11B (B-cell lymphoma/leukemia 11B)
I141V (p.Ile141Val) in BCL11B (B-cell lymphoma/leukemia 11B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
I141V (p.Ile141Val) variant details
- p.Ile141Val
- cosmic curated COSV10591
- ExAC rs772467266
- gnomAD rs772467266
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.03
- CADD 19.60
- PolyPhen-2 0.01
- SIFT 0.17
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available