G143V (p.Gly143Val) variant of BCL11B (B-cell lymphoma/leukemia 11B)
G143V (p.Gly143Val) in BCL11B (B-cell lymphoma/leukemia 11B) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
G143V (p.Gly143Val) variant details
- p.Gly143Val
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.13
- CADD 29.10
- PolyPhen-2 0.12
- SIFT 0.02
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available