D122N (p.Asp122Asn) variant of BCL11B (B-cell lymphoma/leukemia 11B)
D122N (p.Asp122Asn) in BCL11B (B-cell lymphoma/leukemia 11B) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
D122N (p.Asp122Asn) variant details
- p.Asp122Asn
- NCI-TCGA Cosmic COSV6173
- cosmic curated COSV61734
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.09
- CADD 23.40
- PolyPhen-2 0.11
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available