A157T (p.Ala157Thr) variant of BCL11B (B-cell lymphoma/leukemia 11B)
A157T (p.Ala157Thr) in BCL11B (B-cell lymphoma/leukemia 11B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A157T (p.Ala157Thr) variant details
- p.Ala157Thr
- gnomAD rs1444761438
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.05
- CADD 17.90
- PolyPhen-2 0.00
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available