L8I (p.Leu8Ile) variant of BCL10 (B-cell lymphoma/leukemia 10)
L8I (p.Leu8Ile) in BCL10 (B-cell lymphoma/leukemia 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data.
L8I (p.Leu8Ile) variant details
- p.Leu8Ile
- cosmic curated COSV10099
- gnomAD rs1229802365
- Missense
- Variant Prioritization Score for Impact Estimate 0.771
- CADD 25.00
- PolyPhen-2 0.98
- SIFT 0.13
- Most common in the South Asian population (allele frequency 1.2e-05)