K77E (p.Lys77Glu) variant of BCL10 (B-cell lymphoma/leukemia 10)
K77E (p.Lys77Glu) in BCL10 (B-cell lymphoma/leukemia 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
K77E (p.Lys77Glu) variant details
- p.Lys77Glu
- TOPMed rs1383124410
- gnomAD rs1383124410
- Missense
- Variant Prioritization Score for Impact Estimate 0.485
- MetaLR 0.04
- MetaSVM -1.09
- CADD 24.10
- PolyPhen-2 0.28
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.7e-05)
- Structural context available