I55M (p.Ile55Met) variant of BCL10 (B-cell lymphoma/leukemia 10)
I55M (p.Ile55Met) in BCL10 (B-cell lymphoma/leukemia 10) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data.
I55M (p.Ile55Met) variant details
- p.Ile55Met
- ExAC rs769105226
- TOPMed rs769105226
- gnomAD rs769105226
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- MetaLR 0.25
- MetaSVM -0.48
- CADD 25.10
- PolyPhen-2 1.00
- SIFT 0.01
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)