I46V (p.Ile46Val) variant of BCL10 (B-cell lymphoma/leukemia 10)
I46V (p.Ile46Val) in BCL10 (B-cell lymphoma/leukemia 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data.
I46V (p.Ile46Val) variant details
- p.Ile46Val
- gnomAD rs1398422300
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- MetaLR 0.04
- MetaSVM -1.08
- CADD 23.50
- PolyPhen-2 0.99
- SIFT 0.12
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)