E89A (p.Glu89Ala) variant of BCL10 (B-cell lymphoma/leukemia 10)
E89A (p.Glu89Ala) in BCL10 (B-cell lymphoma/leukemia 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
E89A (p.Glu89Ala) variant details
- p.Glu89Ala
- ESP rs368393957
- ExAC rs368393957
- TOPMed rs368393957
- gnomAD rs368393957
- Missense
- Variant Prioritization Score for Impact Estimate 0.506
- MetaLR 0.11
- MetaSVM -1.05
- CADD 23.20
- PolyPhen-2 0.86
- SIFT 0.71
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available