A20P (p.Ala20Pro) variant of BCL10 (B-cell lymphoma/leukemia 10)
A20P (p.Ala20Pro) in BCL10 (B-cell lymphoma/leukemia 10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
A20P (p.Ala20Pro) variant details
- p.Ala20Pro
- gnomAD 1-85270906-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.635
- MetaLR 0.12
- MetaSVM -1.04
- CADD 28.90
- PolyPhen-2 0.97
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available