G11W (p.Gly11Trp) variant of BAX (Apoptosis regulator BAX)
G11W (p.Gly11Trp) in BAX (Apoptosis regulator BAX) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G11W (p.Gly11Trp) variant details
- p.Gly11Trp
- ExAC rs770934324
- TOPMed rs770934324
- gnomAD rs770934324
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.07
- CADD 26.90
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available