S16F (p.Ser16Phe) variant of B2M (Beta-2-microglobulin)
S16F (p.Ser16Phe) in B2M (Beta-2-microglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
S16F (p.Ser16Phe) variant details
- p.Ser16Phe
- TOPMed rs1435611656
- gnomAD rs1435611656
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- MetaLR 0.01
- MetaSVM -0.93
- CADD 17.10
- PolyPhen-2 0.12
- SIFT 0.73
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available