S16C (p.Ser16Cys) variant of B2M (Beta-2-microglobulin)
S16C (p.Ser16Cys) in B2M (Beta-2-microglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
S16C (p.Ser16Cys) variant details
- p.Ser16Cys
- TOPMed rs1435611656
- gnomAD rs1435611656
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- MetaLR 0.01
- MetaSVM -0.91
- CADD 15.60
- PolyPhen-2 0.01
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available