S14F (p.Ser14Phe) variant of B2M (Beta-2-microglobulin)
S14F (p.Ser14Phe) in B2M (Beta-2-microglobulin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes structural context.
S14F (p.Ser14Phe) variant details
- p.Ser14Phe
- rs986783978
- NCI-TCGA TCGA novel
- gnomAD rs986783978
- Variant assessed as somatic; high impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- AlphaMissense 0.13
- MetaLR 0.00
- MetaSVM -0.92
- PolyPhen-2 0.00
- SIFT 0.67
- MutPred 0.50
- UniProt: Variant assessed as somatic; high impact.
- Structural context available