R32H (p.Arg32His) variant of B2M (Beta-2-microglobulin)
R32H (p.Arg32His) in B2M (Beta-2-microglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
R32H (p.Arg32His) variant details
- p.Arg32His
- TOPMed rs2086930091
- gnomAD rs2086930091
- Missense
- Variant Prioritization Score for Impact Estimate 0.748
- CADD 25.20
- PolyPhen-2 0.54
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available