L7F (p.Leu7Phe) variant of B2M (Beta-2-microglobulin)
L7F (p.Leu7Phe) in B2M (Beta-2-microglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
L7F (p.Leu7Phe) variant details
- p.Leu7Phe
- ExAC rs766716677
- gnomAD rs766716677
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- MetaLR 0.01
- MetaSVM -0.90
- CADD 8.30
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available