K39T (p.Lys39Thr) variant of B2M (Beta-2-microglobulin)
K39T (p.Lys39Thr) in B2M (Beta-2-microglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
K39T (p.Lys39Thr) variant details
- p.Lys39Thr
- gnomAD 15-44715471-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.612
- CADD 24.10
- PolyPhen-2 0.60
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available