I27F (p.Ile27Phe) variant of B2M (Beta-2-microglobulin)
I27F (p.Ile27Phe) in B2M (Beta-2-microglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
I27F (p.Ile27Phe) variant details
- p.Ile27Phe
- gnomAD 15-44715434-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- CADD 8.90
- PolyPhen-2 0.08
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available