A6T (p.Ala6Thr) variant of B2M (Beta-2-microglobulin)
A6T (p.Ala6Thr) in B2M (Beta-2-microglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A6T (p.Ala6Thr) variant details
- p.Ala6Thr
- ExAC rs763258605
- gnomAD rs763258605
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- MetaLR 0.01
- MetaSVM -0.90
- CADD 0.28
- PolyPhen-2 0.00
- SIFT 0.68
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available