A6S (p.Ala6Ser) variant of B2M (Beta-2-microglobulin)
A6S (p.Ala6Ser) in B2M (Beta-2-microglobulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A6S (p.Ala6Ser) variant details
- p.Ala6Ser
- ExAC rs763258605
- gnomAD rs763258605
- Missense
- Variant Prioritization Score for Impact Estimate 0.114
- MetaLR 0.01
- MetaSVM -0.89
- CADD 0.14
- PolyPhen-2 0.04
- SIFT 0.81
- Population evidence available
- Structural context available