Y8F (p.Tyr8Phe) variant of AURKB (Aurora kinase B)
Y8F (p.Tyr8Phe) in AURKB (Aurora kinase B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
Y8F (p.Tyr8Phe) variant details
- p.Tyr8Phe
- 1000Genomes rs142567548
- ESP rs142567548
- ExAC rs142567548
- TOPMed rs142567548
- Missense
- Variant Prioritization Score for Impact Estimate 0.582
- CADD 18.40
- PolyPhen-2 0.02
- SIFT 0.59
- Most common in the HGDP:MANDENKA population (allele frequency 0.025)
- Structural context available