R81H (p.Arg81His) variant of AURKB (Aurora kinase B)
R81H (p.Arg81His) in AURKB (Aurora kinase B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
R81H (p.Arg81His) variant details
- p.Arg81His
- cosmic curated COSV10588
- TOPMed rs1016005962
- gnomAD rs1016005962
- Missense
- Variant Prioritization Score for Impact Estimate 0.771
- CADD 27.10
- PolyPhen-2 0.31
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available