P9L (p.Pro9Leu) variant of AURKB (Aurora kinase B)
P9L (p.Pro9Leu) in AURKB (Aurora kinase B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
P9L (p.Pro9Leu) variant details
- p.Pro9Leu
- ESP rs148452780
- ExAC rs148452780
- TOPMed rs148452780
- gnomAD rs148452780
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- CADD 21.80
- PolyPhen-2 0.01
- SIFT 0.06
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available