V19A (p.Val19Ala) variant of AURKA (Aurora kinase A)
V19A (p.Val19Ala) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
V19A (p.Val19Ala) variant details
- p.Val19Ala
- TOPMed rs1475776989
- gnomAD rs1475776989
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.10
- CADD 4.90
- PolyPhen-2 0.01
- SIFT 0.54
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available