S89F (p.Ser89Phe) variant of AURKA (Aurora kinase A)
S89F (p.Ser89Phe) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
S89F (p.Ser89Phe) variant details
- p.Ser89Phe
- gnomAD rs1320396487
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.15
- CADD 15.20
- PolyPhen-2 0.34
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available