S54F (p.Ser54Phe) variant of AURKA (Aurora kinase A)
S54F (p.Ser54Phe) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S54F (p.Ser54Phe) variant details
- p.Ser54Phe
- cosmic curated COSV57167
- TOPMed rs1986382866
- gnomAD rs1986382866
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.06
- CADD 22.20
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available