R90T (p.Arg90Thr) variant of AURKA (Aurora kinase A)
R90T (p.Arg90Thr) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
R90T (p.Arg90Thr) variant details
- p.Arg90Thr
- gnomAD rs1376513260
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.05
- CADD 2.84
- PolyPhen-2 0.42
- SIFT 0.15
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available