R56S (p.Arg56Ser) variant of AURKA (Aurora kinase A)
R56S (p.Arg56Ser) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R56S (p.Arg56Ser) variant details
- p.Arg56Ser
- ESP rs375420005
- ExAC rs375420005
- TOPMed rs375420005
- gnomAD rs375420005
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.07
- CADD 19.10
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available