R3* (p.Arg3Ter) variant of AURKA (Aurora kinase A)
R3* (p.Arg3Ter) in AURKA (Aurora kinase A) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R3* (p.Arg3Ter) variant details
- p.Arg3Ter
- cosmic curated COSV53860
- TOPMed rs1488214455
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.408
- CADD 36.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available