R24H (p.Arg24His) variant of AURKA (Aurora kinase A)
R24H (p.Arg24His) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R24H (p.Arg24His) variant details
- p.Arg24His
- cosmic curated COSV57167
- ExAC rs779597046
- TOPMed rs779597046
- gnomAD rs779597046
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.26
- CADD 22.80
- PolyPhen-2 0.17
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00052)
- Structural context available