R24C (p.Arg24Cys) variant of AURKA (Aurora kinase A)
R24C (p.Arg24Cys) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
R24C (p.Arg24Cys) variant details
- p.Arg24Cys
- cosmic curated COSV10045
- 1000Genomes rs188825988
- ExAC rs188825988
- TOPMed rs188825988
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- REVEL 0.39
- CADD 23.10
- PolyPhen-2 0.17
- SIFT 0.03
- Most common in the HGDP:DAI population (allele frequency 0.056)
- Structural context available