P36L (p.Pro36Leu) variant of AURKA (Aurora kinase A)
P36L (p.Pro36Leu) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
P36L (p.Pro36Leu) variant details
- p.Pro36Leu
- ExAC rs763948949
- gnomAD rs763948949
- Missense
- Variant Prioritization Score for Impact Estimate 0.0712
- REVEL 0.03
- CADD 9.14
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available