P103L (p.Pro103Leu) variant of AURKA (Aurora kinase A)
P103L (p.Pro103Leu) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
P103L (p.Pro103Leu) variant details
- p.Pro103Leu
- ExAC rs748900943
- gnomAD rs748900943
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.16
- CADD 17.80
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available