N93S (p.Asn93Ser) variant of AURKA (Aurora kinase A)
N93S (p.Asn93Ser) in AURKA (Aurora kinase A) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely benign in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
N93S (p.Asn93Ser) variant details
- p.Asn93Ser
- TOPMed rs1420463153
- gnomAD rs1420463153
- Likely benign
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.068
- REVEL 0.06
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.97
- ClinVar: Likely benign (not specified)
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available