L79F (p.Leu79Phe) variant of AURKA (Aurora kinase A)
L79F (p.Leu79Phe) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
L79F (p.Leu79Phe) variant details
- p.Leu79Phe
- cosmic curated COSV10815
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.11
- CADD 13.20
- PolyPhen-2 0.49
- SIFT 0.40
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available