L37S (p.Leu37Ser) variant of AURKA (Aurora kinase A)
L37S (p.Leu37Ser) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L37S (p.Leu37Ser) variant details
- p.Leu37Ser
- TOPMed rs1313879008
- gnomAD rs1313879008
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.12
- CADD 14.70
- PolyPhen-2 0.01
- SIFT 0.30
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available