L26F (p.Leu26Phe) variant of AURKA (Aurora kinase A)
L26F (p.Leu26Phe) in AURKA (Aurora kinase A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
L26F (p.Leu26Phe) variant details
- p.Leu26Phe
- TOPMed rs1986397208
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.04
- CADD 13.60
- PolyPhen-2 0.49
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available